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Alphabetical Index
Cancer Antigen-125, serum (8000100304)
Test Mnemonic:

CA-125
Specimen Requirements:
Collection:

7 mL of blood in SST or red-topped vacutainer tube.  
Minimum Volume:

3mL
Storage/Transport:

Delivered to Sample Management within 2 hours of collection.
Stability:

Room temperature    for ≤ eight hours;   refrigerate for ≤ 48 hours. If the assay will not be completed within 48 hours, or for shipment of samples, freeze a -20°C or colder. (Avoid repeated freeze/thaw cycles).         
Causes for Rejection:

Incomplete and/or incorrect sample identification, improper storage/transport and gross hemolysis or lipemia.                                               
Specimen Preparation:

Allow specimen to clot completely at room temperature. Centrifuge to separate serum from cells within 2 hours of collection. Transfer serum from collection tube to labeled plastic transport tube. 
Methodology:

Chemiluminescence
Performed:

Special Chemistry;   Monday through Friday: 7am – 3:30 pm
Turnaround Time:

M-F: within 24 hours
Reference Range:

 

By report (reports may vary based on instrumentation, patient age and sex).

 
CPT 4 Code:

86304   
Note:

 CA-125 is often elevated in active epithelial and other ovarian cancers. It may be elevated in benign disorders such as pericarditis, cirrhosis, severe endometriosis, first trimester of pregnancy, and ovarian cysts.  Not available on Week-ends.
Effective Date: 03/05/2013
Reviewed By/Date: Okorodudu, Anthony - 02/17/2019
Approved By/Date: Okorodudu, Anthony - 12/20/2022
When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.

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