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Alphabetical Index


Legionella & Streptococcus pneumoniae urinary antigens (8000101657)
Test Mnemonic:

C LUA SP ANT

Specimen Requirements:
Collection:

Collect urine sample in a sterile, leakproof container

Container:

Sterile cup, container or Boric acid preservative tube

Minimum Volume:

5 mL

Storage/Transport:

Refrigerate if delay in transport

Stability:

7 days refrigerated

Causes for Rejection:

Leaking or broken container, incomplete labeling or mislabeled container, missing collection information, submission of more than one specimen

Specimen Preparation:

Submit to laboratory in sterile, leakproof container or transfer specimen to urine preservative tube

Methodology:

Lateral flow immunochromatographic assay

Performed:
Lab:

Clinical Microbiology

Turnaround Time:

4 hours

Reference Range:

Negative

CPT 4 Code:

87899

Note:

Current American Academy of Pediatrics Red Book recommendations note that detection of S. pneumoniae is not useful in children because asymptomatically colonized children may have positive test results.

S. pneumoniae vaccine may cause false positive results up to 10 days after vaccination.

Administration of antibiotics might influence the test results for S. pneumoniae.

A negtive result does not exclude an S. pneumoniae infection. The result of this test as well as culture, serology, or other antigen detection methods should be used in conjunction with clinical findings to make an accurate diagnosis.

A negative result does not exclude the possibility of a Legionella infection, as it can be caused by other serogroups and Legionella species. There is no single satisfactory laboratory test for Legionnaires' Disease. Therefore, culture results, PCR, serology, and/or antigen detection methods should be used in conjunction with clinical findings to make an accurate diagnosis.

False results may occur from highly basic (pH>=9) urine and give false positive S. pneumoniae results. Water-based personal lubricant might result in false positive L. pneumophila when found in the sample at hight levels. 

 

Synonyms:

Legionella antigen, Streptococcus pneumoniae antigen, Strep pneumo urine antigen

Clinical Indication:

Rapid diagnosis of pneumonia caused by Legionella pneumophila serogroup 1 and S. pneumoniae

Effective Date: 04/18/2023
Reviewed By/Date: -
Approved By/Date: Williams-Bouyer, Natalie - 06/09/2023
When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.