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Alphabetical Index
Respiratory Panel by PCR (8000101169)
Test Mnemonic:

RPPCR
Specimen Requirements:

Nasopharyngeal (NP) swab in viral/universal transport media
Test Included:

Panel for the detection of:

  • Adenovirus
  • Coronavirus 229E
  • Coronavirus HKU1
  • Coronavirus NL63
  • Coronavirus OC43
  • Human Metapneumovirus
  • Human Rhinovirus/Enterovirus
  • Influenza A, including subtypes H1, H1-2009, and H3
  • Influenza B
  • Parainfluenza Virus 1
  • Parainfluenza Virus 2
  • Parainfluenza Virus 3
  • Parainfluenza Virus 4
  • Respiratory Syncytial Virus
  • Bordetella parapertussis (IS1001)
  • Bordetella pertussis (ptxP)
  • Chlamydia pneumoniae
  • Mycoplasma pneumoniae
Collection:

Standard collection and handling procedures used to collect nasopharyngeal swab are appropriate.  Swabs are placed into viral/universal transport media.
Container:

NP swab – swab in viral/universal transport media
Minimum Volume:

1 mL
Storage/Transport:

Specimen should be delivered to the lab ASAP.  Storage for up to 4 hours at room temperature; then, refrigerate.
Stability:

Refrigerated up to 3 days.
Causes for Rejection:

Specimens must meet criteria set forth in the Laboratory Services Specimen Labeling and Requests for Testing policy.

Specimens are canceled as duplicates if the patient was previously tested:   

            - Within 7 days – Pediatric patient (< 12 years old).

            - Within 14 days – Adult patient.

This test is primarily for use on hospitalized pediatric and adult patients. Prior approval is required on adult patients by the Critical Care and Infectious Diseases specialties. 

Specimens may be canceled as duplicates if the patient has tested positive for influenza A, influenza B, RSV and/or COVID-19.
Methodology:

Multiplex Polymerase Chain Reaction (PCR)
Performed:
Lab:

Clinical Microbiology
Turnaround Time:

1 - 2 days
Reference Range:

Negative
CPT 4 Code:

87633

87798 x 2

87486

87581
Note:

A negative result should not rule-out infection in patients with a high pretest probability for respiratory infection.  The assay does not test for all potential infectious agents of respiratory infection.

Positive results do not distinguish between a viable organism and the presence of a nonviable organism or nucleic acid.

Results of the panel are intended to aid in the diagnosis of illness and are meant to be used in conjunction with other clinical and epidemiological findings.

There may be public health requirements that requires reporting as a notifiable condition.

NP viral/universal transport collection kits available through Materials Management or by contacting Laboratory Client Services.
Synonyms:

Adeno, ADV, Adenovirus, Coronavirus, hMPV, MPV, Human Metapneumovirus, Metapneumovirus, Rhinovirus, Enterovirus, EV, Influenza, Influenza A, Influenza B, Flu A, Flu B, Flu, Parainfluenza, Paraflu, PIV, Respiratory Syncytial Virus, RSV, Bordetella, Bordetella parapertussis, Bordetella pertussis, Whooping, Whooping cough, Pertussis, Chlamydia pneumoniae, Chlamydophila, Mycoplasma, Mycoplasma pneumoniae, Upper Respiratory, Respiratory Virus
Clinical Indication:

This test is used to detect respiratory pathogens – adenovirus, coronavirus, human metapneumovirus, human rhinovirus/enterovirus, influenza A, influenza B, parainfluenza, respiratory syncytial virus, Bordetella parapertussis, Bordetella pertussis, Chlamydia pneumoniae, and Mycoplasma pneumoniae.
Effective Date: 11/05/2021
Reviewed By/Date: Williams-Bouyer, Natalie - 08/21/2019
Approved By/Date: Williams-Bouyer, Natalie - 02/12/2024
When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.

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